Quality document guide
What a peptide COA should tell the buyer
A useful certificate of analysis connects the named material and batch to an agreed specification, test methods, results and release responsibility.
Check identity, batch number, specification version, tests, methods, acceptance limits, actual results, issue date, release status and authorized issuer. Then decide which supporting data must accompany the COA.
Core fields
Minimum information for a reviewable COA
- Material name and identity convention
- Batch or lot number
- Specification or method reference
- Test item and acceptance limit
- Actual result and units
- Issue date and release status
- Authorized issuer or quality function
- Storage or retest information where applicable
Questions beyond the COA
| Identity | Does the buyer require MS or another identity method? |
|---|---|
| Purity | Which HPLC method, detection condition and integration rules apply? |
| Content | Is the buyer asking for purity, assay, peptide content or another defined measure? |
| Impurities | Are individual impurity limits or related-substance reporting required? |
| Raw data | Are chromatograms, spectra, calculation sheets or electronic raw data required? |
Important: A representative COA illustrates a document route; it does not release a future commercial batch.
FAQ
COA review questions
Agree the evidence package before sampling.
Should a peptide COA identify the batch?
Yes. A lot-specific COA should connect the named material and batch to the reported methods, results, release decision and issue information.
Does a COA replace HPLC or MS data?
Not necessarily. The buyer should define whether chromatograms, spectra, raw data or method details are required in addition to summarized COA results.